Answer
Not possible.
Work Step by Step
$\frac{x^2+4x+4}{x^2-5x+4}=\frac{(x+2)^2}{(x-4)(x-1)}$
$x=4$ and $x=1$ are not zeros of the numerator, thus it is not possible to simplify the fraction further.
You can help us out by revising, improving and updating this answer.
Update this answerAfter you claim an answer you’ll have 24 hours to send in a draft. An editor will review the submission and either publish your submission or provide feedback.