Answer
$100$
Work Step by Step
The order of operations follow the PEMDAS rule:
First Priority: P - Parentheses or grouping symbols
Second Priority: E - Exponents
Third Priority: M/D - Multiplication or division, whichever comes first from the left
Fourth Priority: A/S - Addition or subtraction, whichever comes first from the left
Simplify within the parentheses to have:
$=(2\cdot 2 \cdot 2 \cdot 2 - 6)^2
\\=(16-6)^2
\\=10^2$
Apply the exponent to have:
$=10(10)
\\=100$
