Answer
$108$ square inches
Work Step by Step
First you need to find the area of the white space, which is a rectangle with length $7$ inches and width $5$ inches, so the area of the white space is $35$ square inches. Then, you have to find the area of the picture frame and the picture combined, which has a length of $7+6 = 13$ inches and a width of $5+6 = 11$ inches. $ 13 \times 11$ is $143$, so the area is $143 in^2$. Subtract 143 and 35 and you get $\boxed{108}$
