Frederick Tarr
As his eponymous name suggests, Frederick Tarr is one of the two main protagonists of the tale. An Englishman who potentially acts as a mouthpiece for Wyndham Lewis's artistic principles, Tarr's characterization is equal parts cynical and self-parodic. He is shrewd, articulate with a Nietzschean outlook on the world.
Bertha
Tarr's German girlfriend is characterized as sentimental, and as a satire upon German tropes. She is maltreated by both Tarr and Kriesler, and is raped by the latter. As the plot progresses she becomes increasingly disheveled, a shell of her former self.
Otto Kriesler
The second main protagonist, Otto Kriesler is a German romantic. He lives off of his father's allowance, and is the antithesis of Tarr: easily mislead and a failed artist. His love of Anastaysa drives him into a spiral of madness, culminating in his eventual suicide.
Anastaysa
A focal point of the romantic affections of the two male protagonists of the tale, Anastaysa is the female counterpart to Tarr in many respects. She is intellectually astute,
Soltyk
A Polishman who acts as the main antagonist to Kriesler after the latter believes he is courting Anastaysa. He is accidentally murdered by Kriesler in a duel.
Rose Fawcett
Mentioned briefly in the coda of the novel, Rose Fawcett is revealed to be the eventual wife of Tarr.
Prism Dirkes
Mentioned briefly in the final sentence of the novel, Prism Dirkes is revealed to be the potential adulterous lover of Tarr.