Colonialism
The novel is set in California just after the Mexican-American War. It portrays the attitude of Mexicans through the character of Senora Gonzaga Moreno who hates Ramona because she is a mixed Native American. Thus, historically it is very important because, as a colonized people, Mexicans wanted to maintain their culture by avoiding the United States, but at the end Americans won the war.
Helpless situation of Native Americans
The narrative also shows the powerlessness of Native American through Ramona and Alessandro. They elope to find peace and comfort but falls in adverse circumstances and losses the sanity. Thus, H. H. Jackson raises voice against the pitiable condition of Native American and makes all the Americans the villains.
Feminism
Ramona is very strong character. She understands that Senora Gonzaga Moreno does not love as her daughter. She goes against her and elopes with Alessandro. Later, she keeps her mental strength. Not only she loves her child and named her Ramona. Again, she takes a big decision though she loves Alessandro; she marries her half brother Felipe Moreno. Felipe knows that Ramona loves Alessandro but Felipe also loves her. At last, she leads a happy life.
Love
There are various instances of love relations. However, those loves worth mentioning are relationship between Alessandro and Ramona and between Felipe and Ramona. Alessandro and Ramona elope to find happiness. No Americans offer them to stay; they are driven by Americans and finally settle in the San Bernardino Mountains. Alessandro is a handsome young man goes insane in the adverse situation of their life but still she loves him and cares about him and their child. After he died, Ramona marries Felipe. In spite of knowing that she loves Alessandro more than him, Felipe loves her and her child; thus, they lead a very happy life.