David Sedaris
This humorist is also the main protagonist in each of these essays and stories. This collection is mostly David reflecting on family, his history with being gay and coming out to his family.
Hugh
This is David's long-time boyfriend who shows up as a character in a few of the stories ("A Can of Worms," "The End of the Affair").
Lisa
This is David's sister. He explores the story of their friendship, but also the tension in their relationship, in the story, "Repeat After Me."
Tiffany
One of David's sisters. This relationship is explored in the essay/story, "Put a Lid on It" when David visits her at her home, and the two get to talking.
David's brother
David details what it is like to have a little brother. His little brother appears as a character in his essay, "Rooster at the Hitchin' Post" and also in "Baby Einstein" when this brother has his first child with his wife.