- Caroline "Carrie" Meeber, a.k.a. Carrie Wheeler and Carrie Madenda, the latter her stage name
- Minnie Hanson, Carrie's elder sister
- Sven Hanson, Minnie's husband
- Charles H. Drouet, a buoyant traveling salesman
- George W. Hurstwood, a.k.a. George Wheeler
- Julia Hurstwood, George's strong-willed, social-climbing wife
- Jessica Hurstwood, George's daughter
- George Hurstwood, Jr, George's son
- Mr. and Mrs. Vance, a wealthy merchant and his vivacious young wife, who live in the same building as Hurstwood and Carrie in New York City. Mrs. Vance and Carrie become friends.
- Robert Ames, Mrs. Vance's cousin from Indiana, a handsome young scholar whom Carrie regards as a male ideal
- Lola Osborne, a friendly chorus girl Carrie meets during a theatre production. She provides helpful advice, then seeing that Carrie shows much promise, becomes her "satellite".
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