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Aslan
Sorry this is only a short answer space but I can give you a general comment.
They both feel unsafe. They think that they will be the logical targets of guilt over their father king's murder, 'the near in blood, the nearer bloody. ' People will think they killed King Duncan to further their succession to the throne. Donalbain flees to Ireland and Malcolm flees to England. This temporarily works in Macbeth's favour.