Without naming names, who in general on Earth have been great fighters of the Dark Thing?

When Calvin asks who the fighters had been, Mrs. Who relates a quote: “And the light shineth in darkness; and the darkness comprehended it not.” Charles Wallace recognizes this as Jesus, and Mrs. Whatsit tells him yes, along with other great artists and scientists and thinkers such as da Vinci and Shakespeare and Einstein, as well as Buddha, Beethoven, Rembrandt, and St. Francis.